The present article explore about the stress of nurses facing in the work place especially in the health care setting. Every day nurses face lots of stress and obstacle and over come the stress is the major challenge for them. Due to stress nurses face harmful effect both physically and mentally. It is very essential to minimize the stress and enhance or boost up our internal strength to eliminate it from our carrier. Nurses can adopt various technique to relax herself, whenever she feel stress. In this article we can see about stress and its effects and the way to over come it in detailed manner.